
背景知识:SOD是超氧化物岐化酶(superoxidedimutase)的简称,是一种广泛存在于动物、植物和微生物中的生物酶,是目前公认的重要的氧自由基清除剂。20世纪自由基学说的提出使SOD的提取及应用得到国内外生化界和医药界的极大关注。研究证实,在SOD高效催化作用下,自由基可被岐化为双氧水和氧,在清除剂的协同作用下使之成为水和新生氧,从而彻底清除体内过剩的氧自由基。目前SOD在医学临床上用于治疗癌症、炎症、高血压、心脏病、糖尿病等近百种疾病,对防辐射、抗氧中毒、防化疗损伤等具有独特效益,特别是抗衰老作用明显,并在保健品、化妆品、航天、军事医学等方面得到广泛应用。
Antioxidant Ingredient Proven To Relieve Stress
抗氧化成分被证明有助于缓解压力
来源:http://www.sciencedaily.com/releases/2009/09/090914194652.htm
转自丁香园dallas翻译
ScienceDaily (Sep. 15, 2009) — A dietary ingredient derived from a melon rich in antioxidant superoxide dismutase enzymes has been shown to relieve stress. In a double-blind, randomised, placebo-controlled trial, published in BioMed Central's open access Nutrition Journal, researchers found that the supplement decreased the signs and symptoms of perceived stress and fatigue in healthy volunteers.
科学日报(2009年9月15日)— 从含丰富抗氧化剂超氧化物岐化酶的瓜类中提取的一种成份被证明可以缓解压力。据发表于生物医学中心(BioMed Central)上可公开查阅的《营养》杂志的一项随机对照双盲研究称,研究者们发现补充该抗氧化成分可缓解健康志愿者们表现出的压力与疲劳的症状、体征。
Marie-Anne Milesi from Seppic, France, worked with a team of researchers to evaluate its anti-stress effects in 70 volunteers. She said: "Several studies have shown that there is a link between psychological stress and intracellular oxidative stress. We wanted to test whether augmenting the body's ability to deal with oxidative species might help a person's ability to resist burnout. The 35 people in our study who received capsules containing superoxide dismutase showed improvement in several signs and symptoms of perceived stress and fatigue."
来自法国Seppic公司的Marie-Anne Milesi与一组研究团队合作在70个志愿者中评估该抗氧化成分的抗压力效果。她说:“数项研究已经表明心理压力与细胞内氧化效应有关。我们想证明提高机体处理氧化物的能力是否有助于增强个体抵抗压力的能力。在我们的研究中,35个服用含超氧化物歧化酶胶囊的受试者表现出的压力、疲劳症状和体征得到改善。
The researchers found a strong placebo effect in the volunteers who received inactive starch capsules, as can be expected when studying subjective feelings like stress. However, the improvements seen in the supplement group were significantly greater, especially after 28 days.
研究者们在服用无活性淀粉胶囊的志愿者中发现了强烈的安慰剂效应,这在研究主管感受如紧张的研究中是可预期的。然而,在实验组中表现出的症状体征的改善更明显,尤其在服用28天后。
According to Milesi: "The placebo effect was only present during the first 7 days of supplementation and not beyond. It will be interesting to confirm these effects and better understand the action of antioxidants on stress in further studies with a larger number of volunteers and a longer duration."
Milesi说:“安慰剂效应仅在服用安慰剂的前七天内出现,超过七天后不会再有安慰剂效应。在未来的研究中纳入更多的志愿者并研究更长的时间以进一步确证并更好的了解抗氧化剂的缓解压力的作用,这将会是一件有趣的事情。”
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