
转自丁香园动态版 scutf编译
Biotransformed Blueberry Juice Fights Fat And Diabetes
ScienceDaily (Sep. 2, 2009) — Juice extracted from North American lowbush blueberries, biotransformed with bacteria from the skin of the fruit, holds great promise as an anti-obesity and anti-diabetic agent.
生物转化的蓝莓汁有助于治疗肥胖和糖尿病
科学日报(2009年9月2日)—由水果表面的细菌转化的北美矮丛蓝莓汁很有希望有助于治疗肥胖和糖尿病。
原文:http://www.sciencedaily.com/releases/2009/09/090901105153.htm
The study, published in the International Journal of Obesity, was conducted by researchers from the Université de Montréal, the Institut Armand-Frappier and the Université de Moncton who tested the effects of biotransformed juices compared to regular blueberry drinks on mice.
加拿大蒙特利尔大学、阿曼德—弗雷皮尔研究所以及蒙克顿大学的学者联合进行了一项研究,考察了生物转化的蓝莓汁和普通蓝莓汁对老鼠的影响,研究结果刊登于国际肥胖杂志。
"Results of this study clearly show that biotransformed blueberry juice has strong anti-obesity and anti-diabetic potential," says senior author Pierre S. Haddad, a pharmacology professor at the Université de Montréal's Faculty of Medicine. "Biotransformed blueberry juice may represent a novel therapeutic agent, since it decreases hyperglycemia in diabetic mice and can protect young pre-diabetic mice from developing obesity and diabetes."
“研究结果清楚的表明了生物转化的蓝莓汁对于治疗肥胖和糖尿病大有潜力”,蒙特利尔大学药学系药理学教授资深专家Pierre S. Haddad说,“生物转化的蓝莓汁或许能够成为一种新型的治疗药物,它可以降低糖尿病老鼠的血糖,而且能够防止处于前糖尿病期的年轻老鼠患上肥胖和糖尿病。
The scientists tested the effect of biotransformed blueberry juice on a group of mice prone to obesity, insulin resistance, diabetes and hypertension. Incorporating biotransformed blueberry juice into the water of mice reduced their food intake and their body weight. "These mice were an excellent model that closely resembles obesity and obesity-linked type 2 diabetes in humans," says Dr. Haddad, who is also director of the CIHR Team in Aboriginal Anti-Diabetic Medicines at the Université de Montréal.
科学家们试验了生物转化的蓝莓汁对有肥胖、胰岛素抵抗、糖尿病和高血压趋向的老鼠的作用,他们将蓝莓汁加入到老鼠的引用水中,发现老鼠的食量和体重均降低。“这些老鼠是很好肥胖模型和肥胖型II型糖尿病的模型。”任加拿大卫生研究院本土药物治疗糖尿病药学组主任的Haddad博士说,该研究小组设在蒙特利尔大学。
Biotransformation of the blueberry juice was achieved with a new strain of bacteria isolated from the blueberry flora, specifically called Serratia vaccinii, which increases the fruit's antioxidant effects. "The identification of the active compounds in biotransformed blueberry juice may result in the discovery of promising new antiobesity and antidiabetic molecules," says Dr. Haddad.
将从蓝莓中分离到的乌饭树星沙雷氏菌对蓝莓汁进行生物转化,这可以提高果汁的抗氧化能力。“生物转化的蓝莓汁活性成分的鉴定或许会导致发现一种极有希望的抗肥胖和糖尿病的新型分子实体。”,Haddad博士说。
As for the impact of blueberry products on diabetes, says Tri Vuong, lead author and recent PhD graduate from the Université de Montréal's Department of Pharmacology: "Consumption of fermented blueberry juice gradually and significantly reduced high blood glucose levels in diabetic mice. After three days, our mice subjects reduced their glycemia levels by 35 percent."
至于蓝莓产品对糖尿病的治疗作用,文章的第一作者,刚从蒙特利尔大学药理系博士毕业的Tri Vuong说道:“饮用发酵的蓝莓汁可逐步降低糖尿病老鼠的血糖水平,且降糖作用明显。饮用蓝莓汁3天后,老鼠的高血糖水平降低达35%,
This study was funded by the Canadian Institutes of Health Research, the Atlantic Canada Opportunities Agency and the Fonds de recherche sur la nature et les technologies.
该研究是由加拿大卫生研究院、大西洋地区商机局和Fonds de recherche sur la nature et les technologies资助进行的。
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原文:http://blog.zenmechi.com/post/336.html

