Weight Loss Improves Mood In Depressed People, New Research Shows
减肥可缓解抑郁患者负面情绪

原文链接: http://www.sciencedaily.com/releases/2009/07/090727102028.htm
本文转自www.dxy.cn mRNA编译

ScienceDaily (July 29, 2009) — Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior finds that after a 6-month behavioral weight loss program, depressed patients not only lost 8% of their initial weight but also reported significant improvements in their symptoms of depression, as well as reductions in triglycerides, which are a risk factor for heart disease and stroke. The results of this study highlight the need for further research into the effects of weight loss in individuals suffering from psychiatric disorders.

每日科学( 2009年7月29日) -在吸收相关行为学会的年度会议发表的研究表明:在施行6个月的减肥计划行为后,抑郁症患者不仅减去了8 %的体重,而且还初步报告其抑郁症的症状显著改善,并减少了甘油三脂,这是一个心脏病和中风的危险因素。这项研究的结果显著表明需要进一步研究患有精神疾病的患者体重减轻对其的影响。

“This research is novel because clinically depressed individuals are not usually included in weight loss trials due to concerns that weight loss could worsen their depression,” said Dr. Lucy Faulconbridge, lead author of the study. “These concerns, however, are not based on empirical evidence, and the practice of excluding depressed individuals from clinical weight loss trials means that we are learning nothing about this high-risk population.” The latest findings suggest that depressed, obese individuals can indeed lose clinically significant amounts of weight, and that weight loss can actually reduce symptoms of depression.

“这项研究具有新颖性,因为由于担心体重减轻可能恶化的抑郁症,临床抑郁患者通常不包括在减轻体重试验中。”Faulconbridge领导这一研究的的露西博士说: “然而这些担心并非基于经验主义证据,将临床抑郁症的患者排除在减轻体重试验外的做法意味着我们不了解这一高危人群。 ”最新研究结果显示,肥胖的抑郁症患者确实可以在临床上减轻显著的体重,而且体重下降实际上可以减轻抑郁症状。

Fifty-one depressed and non-depressed subjects were recruited into the study to follow a supervised weight loss program that included lifestyle modification and meal replacements. Both depressed and non-depressed subjects lost significant amounts of weight, with depressed individuals losing 8% of their initial body weight, compared with 11% loss by non-depressed individuals. After 6 months on the weight loss program, depressed subjects also showed significant improvement of their depressive symptoms, based on a questionnaire.

51名抑郁症和非抑郁受试者招募到这项研究中去进行一项有监督的减轻体重计划,其中包括改善生活方式和膳食替代品。所有抑郁和非抑郁受试者都减轻了大量的体重,患有抑郁症的患者减去了8 %的体重,而非抑郁者减去了11 %的体重。经过6个月的减重计划,一项调查问卷表明抑郁受试者的抑郁症状也有显著改善。

Additional significant improvements in glucose, insulin and high density lipoprotein (HDL) cholesterol were observed in both depressed and non-depressed subjects, and depressed individuals showed reduced levels of triglycerides in the blood, which have been linked to risk of heart disease and stroke. “Depression and obesity are independently associated with increased risk of heart disease and stroke, and so reductions in both body weight and symptoms of depression are likely to improve long-term health outcomes” said Faulconbridge.

另外在抑郁和非抑郁症受试者的观察中伴随血糖、胰岛素和高密度脂蛋白( HDL )胆固醇的显着改善,抑郁症患者血液中的甘油三酯水平也在降低,这些都是心脏病和中风的危险因子。 “抑郁症和肥胖症都会独立地增加心脏病和中风等疾病风险,因此减轻体重和改善抑郁症状有可能长期促进健康成果。”Faulconbridge表示道 。

编译


减肥可缓解抑郁患者负面情绪


每日科学( 2009年7月29日) -在吸收相关行为学会的年度会议发表的研究表明:在施行6个月的减肥计划行为后,抑郁症患者不仅减去了8 %的体重,而且还初步报告其抑郁症的症状显著改善,并减少了甘油三脂,这是一个心脏病和中风的危险因素。这项研究的结果显著表明需要进一步研究患有精神疾病的患者体重减轻对其的影响。

“这项研究具有新颖性,因为由于担心体重减轻可能恶化的抑郁症,临床抑郁患者通常不包括在减轻体重试验中。”Faulconbridge领导这一研究的的露西博士说: “然而这些担心并非基于经验主义证据,将临床抑郁症的患者排除在减轻体重试验外的做法意味着我们不了解这一高危人群。 ”最新研究结果显示,肥胖的抑郁症患者确实可以在临床上减轻显著的体重,而且体重下降实际上可以减轻抑郁症状。

51名抑郁症和非抑郁受试者招募到这项研究中去进行一项有监督的减轻体重计划,其中包括改善生活方式和膳食替代品。所有抑郁和非抑郁受试者都减轻了大量的体重,患有抑郁症的患者减去了8 %的体重,而非抑郁者减去了11 %的体重。经过6个月的减重计划,一项调查问卷表明抑郁受试者的抑郁症状也有显著改善。

另外在抑郁和非抑郁症受试者的观察中伴随血糖、胰岛素和高密度脂蛋白( HDL )胆固醇的显着改善,抑郁症患者血液中的甘油三酯水平也在降低,这些都是心脏病和中风的危险因子。 “抑郁症和肥胖症都会独立地增加心脏病和中风等疾病的风险,因此减轻体重和改善抑郁症状有可能长期促进健康成果。”Faulconbridge表示道 。(

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