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Effect of a High-Fiber Diet Compared With a Moderate-Fiber Diet on Calcium and Other Mineral Balances in Subjects With Type 2 Diabetes
T2D选择高纤维素饮食与适量纤维素饮食对钙及其他矿物质平衡的影响

原文：http://care.diabetesjournals.org/content/32/6/990.full 小顾营养编译

Abstract
摘要

OBJECTIVE High levels of dietary fiber, especially soluble fiber, are recommended to lower serum cholesterol levels and improve glycemic control in patients with type 2 diabetes. It is not clear, however, how high levels of fiber affect mineral balance.

目的 高水平的膳食纤维，尤其是可溶性纤维，往往被推荐以降低血清胆固醇水平、协助2型糖尿病患者控制血糖。但是目前尚不清楚高水平的纤维影响矿物质的平衡的情况。

RESEARCH DESIGN AND METHODS In a randomized crossover study, 13 patients with type 2 diabetes were fed a high-fiber (50 g total and 25 g soluble fiber) and a moderate-fiber (24 g total and 8 g soluble fiber) diet of the same energy, macronutrient, calcium, magnesium, and phosphorus content for 6 weeks each. Intestinal calcium absorption was determined by fecal recovery of 47Ca. Stool weight and mineral content were assessed during 3 days, and 24-h urinary mineral content and serum chemistry were assessed over 5 days at the end of each phase. The results were compared by repeated-measures ANOVA.

研究 实用随机交叉研究的设计和方法,13位2型糖尿病患者6周内被喂食高纤维素(50克，25克可溶性纤维总量)和适量纤维素(24克,8克总可溶性纤维)的能量相同的膳食,以及大量营养素、钙、镁、磷。肠道内钙质吸收视粪便中回收的47Ca情况而定。在三天内测定大便的重量和矿物质含量以及24-h尿矿物含量测定，并在5天内的各个阶段收集血清化学分析。结果通过重复量数双因子变异数分析进行了比较。
　
RESULTS Compared with the moderate-fiber diet, the high-fiber diet increased stool weight (165 ± 53 vs. 216 ± 63 g/day, P = 0.02) and reduced 24-h urinary calcium (3.3 ± 1.7 vs. 2.4 ± 1.2 mmol/day, P = 0.003) and phosphorus (29.2 ± 5.5 vs. 26.0 ± 3.2 mmol/day, P = 0.003) excretion and serum calcium concentration (2.33 ± 0.06 vs. 2.29 ± 0.07 mmol/l, P = 0.04). Calcium absorption, stool calcium, magnesium, and phosphorus content and serum phosphorus concentration were not significantly different with the two diets.

结果 相比适当纤维素的饮食、高纤维食物增加了粪便的重量(165 ± 53 vs. 216 ± 63 g/day, P = 0.02) ，并降低24小时尿钙(3.3 ± 1.7 vs. 2.4 ± 1.2 mmol/day, P = 0.003) 、磷(29.2 ± 5.5 vs. 26.0 ± 3.2 mmol/day, P = 0.003)的分泌以及血钙浓度(2.33 ± 0.06 vs. 2.29 ± 0.07 mmol/l, P = 0.04)钙的吸收、粪钙、镁、磷含量和血清无机磷浓度在两种饮食中无明显不同。
　　
CONCLUSIONS A high-fiber diet rich in soluble fiber has a small impact on calcium and phosphorus balance in subjects with type 2 diabetes. It may be prudent to ensure adequate intake of calcium and other minerals in individuals consuming a high-fiber diet.

结论 高可溶性纤维素膳食患有2型糖尿病患者的体内钙磷平衡会有小小的影响，对于采用高纤维素的个人增加充足的钙和其他矿物质的摄入也许是明智的。